Scientists create mouse embryo only from embryonic stem cells

In other words, the team was able to reconstitute the three major tissues of the developing mouse embryo (heart, brain, and the basis for other organs) by starting with only ESCs (Cell Stem Cell, September 8, 2022). They did so by coaxing the ESCs with two extraembryonic lineages of the post-implantation embryo by transcription-factor-mediated induction.

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